Hypericin- and mTHPC-mediated photodynamic therapy for the treatment of cariogenic bacteria
نویسندگان
چکیده
منابع مشابه
Benefits of nanoencapsulation for the hypericin-mediated photodetection and photodynamic therapy of ovarian micrometastases
Ovarian cancer is the fourth most frequent cause of cancer-related death in women in the United States. The currently recommended treatment is a combination of surgery followed by chemotherapy. However, ovarian cancer is characterized by the development of peritoneal micrometastases. These latter, hardly detectable by conventional method, are therefore suboptimally treated by standard surgery. ...
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The phototoxic effect of hypericin can be utilized for Photodynamic Therapy (PDT) of cancer. After intravenous application and systemic distribution of the drug in the patient's body, the tumor site is exposed to light. Subsequently, toxic reactive oxygen species (ROS) are generated, inducing tumor cell death. To prevent unwanted activation of the drug in other regions of the body, patients hav...
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Radical tumor resection is the basis for the prolonged survival of patients suffering from malignant brain tumors such as glioblastoma multiforme. We have carried out a phase-II study involving 22 patients with malignant brain tumors to assess the feasibility and the effectiveness of the combination of intraoperative photodynamic diagnosis and fluorescence-guided resection (FGR) mediated by the...
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ژورنال
عنوان ژورنال: Medical Laser Application
سال: 2009
ISSN: 1615-1615
DOI: 10.1016/j.mla.2009.07.004